The 4th International
BioDesign Research Conference

International Symposium on Development and 
Application of Modern Biotechnology

The 4th International
BioDesign Research Conference

International Symposium on Development and Application of Modern Biotechnology

October 27th - 30th, 2023
Wuhan, China

October 27th - 30th, 2023
Wuhan,China

  Program

Add to calendar IBDRC2021.ics

December 6

Opening Ceremony and General Session
(Moderator: AE Shoshana Wodak, VIB-VUB Center for Structural Biology, Belgium) 

07:30 - 07:50 am  
US Pacific Standard Time

Introduction of BioDesign Research, and welcome remarks (Alfonso Jaramillo)

07:50 - 08:50 am 

AB George Church, Harvard University, USA
BioDesign: from atoms to ecosystems

08:50 - 09:50 am 

AE Michael Elowitz, California Institute of Technology, USA
Multicellular Circuit Design

09:50-10:50 am 

AB David Baker, University of Washington, USA
De novo protein design using deep learning



December 7

(Moderator: Yvonne Y. Chen, University of California, Los Angeles, USA) 
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am
US Pacific Standard Time

AE Mark Isalan, Imperial College London, UK
A genetic toolkit and gene switches to limit Mycoplasma growth for a synthetic vaccine chassis

08:40 - 09:20 am 
AB David Liu, Harvard University, USA
Base Editing and Prime Editing: Precision Gene Correction Without Double-Strand DNA Breaks
09:20 - 10:00 am 

Yvonne Y. Chen, University of California, USA
Engineering Next-Generation CAR-T Cells for Cancer Immunotherapy

10:00 - 10:40 am 

AE Yuan Lu, Tsinghua University, China
Cell-free synthetic biology: An emerging engineering strategy to revolutionize the biodesign

10:40 - 11:20 am 

AE Philipp Holliger, MRC, Cambridge, UK
Evolutionary engineering for synthetic genetics



December 8

(Moderator: EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am 
US Pacific Standard Time

AB AE Rodolphe Barrangou, North Carolina State University, USA
Using diverse CRISPR effectors to manipulate microbiomes

08:40 - 09:20 am 

AE Beatrix Suess, Technical University, Darmstadt, Germany
Synthetic RNA regulatory systems

09:20 - 10:00 am

AE Yue Shen, BGI-Research, China
Synthetic Genomics: Enabling Technologies and Applications

10:00 - 10:40 am

Qiannan Hu, Shanghai Institute of Nutrition and Health, CAS, China
Data-driven de novo Synthetic Biology Pathway Design Systems

10:40 - 11:20 am

AE Tae Seok Moon, Washington University in St. Louis, USA
Systems and synthetic biology: constructing smart and programmable microbes to address global problems



December 9

(Moderator: AB Ron Breaker, Yale University, USA)
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am 
US Pacific Standard Time

AB Ron Breaker, Yale University, USA
The Diversity of Ligands for Natural Riboswitches

08:40 - 09:20 am 

AE Jeff Hasty, University of California San Diego, USA
Design Challenges for Gene Circuits

09:20 - 10:00 am 

Susanna Manrubia, Spanish National Centre for Biotechnology, Spain
How do genotype-phenotype biases condition designability?

10:00 - 10:40 am 

AE Rafael Sanjuan, Institute for Integrative Systems Biology, Valencia, Spain
Cooperative replication in viruses: a social evolution perspective

10:40 - 11:20 am 

AE Peng Xu, Guangdong Technion - Israel Institute of Technology, China
Biomanufacturing and intelligent control systems



December 10

(Moderator: AE Mustafa Khammash, ETH Zurich, Switzerland)
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am 
US Pacific Standard Time

Terry Hwa, University of California San Diego, USA
mechanisms and consequences of bacterial growth control

08:40 - 09:20 am 

AE Mustafa Khammash, ETH Zurich, Switzerland
Biodesign of Genetic Control Systems

09:20 - 10:00 am 

Tara L. Deans, University of Utah, USA
Designing synthetic gene circuits to reprogram cells

10:00 - 10:40 am 

Erik Winfree, California Institute of Technology, USA
Exploiting stochasticity in molecular systems: theory

10:40 - 11:20 am 

AE Jian Xu, Qingdao Institute of Bioenergy and Processes, CAS, China
Ramanome, FlowRACS and RACS-Seq: linking metabolic phenome and genome at single-cell resolution for mining cell factories and enzymes



December 11

Workshop for manuscript writing (Moderator: AE Tae Seok Moon, Washington University in St. Louis, USA)

08:00 - 08:10 am 

AE Tae Seok Moon, Washington Unoversity in St. Louis, USA
Intro of the speakers and the workshop 

08:10 - 08:25 am 

Ruchika Bajaj , University of California San Francisco, USA
Brief description of the paper with slides 

08:25 - 08:40 am 

Q&A and comments on the paper/presentation from the audiences

08:40 - 09:10 am 

Abinaya Badri , Ginkgo Bioworks, Inc., USA
Reviewer comments on the paper and presentation how to write a good paper 



December 13

(Moderator: AE Virginia Cornish, Columbia University, USA)
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am 
US Pacific Standard Time

Kristala L. J. Prather, MIT, USA
Engineered Autonomous Control of Metabolic Pathways

08:40 - 09:20 am 

AE Virginia Cornish, Columbia University, USA
Expanding the synthetic capabilities of yeast

09:20 - 10:00 am 

AE Douglas Densmore, Boston University, USA
Automating the Design of Microfluidic Environments for Bioelectronic Systems

10:00 - 10:40 am 

Tom Ellis, Imperial College London, UK
Patterning grown materials with DNA-programmed properties

10:40 - 11:20 am 

Ricard Sole, Pompeu Fabra University, Spain
Emergent complexity and the limits of bioengineering

11:20 am - 12:00 pm

Jason Chin, University of Cambridge, UK
Reprogramming the Genetic Code



December 14

(Moderator: AE Shoshana Wodak, VIB-VUB Center for Structural Biology, Belgium)
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am

Donald Hilvert, ETH Zurich/Laboratory of Organic Chemistry, Switzerland
Evolving virus-like nucleocapsids in the lab

08:40 - 09:20 am 

Anastassia Vorobieva, VIB-VUB Center for Structural Biology, Belgium
De-novo design of pore-forming transmembrane beta-barrels

09:20 - 10:00 am 

Emmanuel Levy, Weizmann Institute of Science, Israel
Principles of Protein Assembly in Cells

10:00 - 10:40 am 

Anum Glasgow, Columbia University, USA
Computational design of protein binders for new functions

10:40 - 11:20 am 

Sergey Ovchinnikov, Harvard University | Harvard FAS Center for Systems Biology, USA
Inverting protein structure prediction models for protein design



December 15

(Moderator: AE Matthew Porteus, Stanford University, USA)
                       EiC Alfonso Jaramillo, Institute for Integrative Systems Biology, Valencia, Spain)

08:00 - 08:40 am 
US Pacific Standard Time

AE Matthew Porteus, Stanford University, USA
Biodesign through the Broad Use of Homology Directed Genome Editing

08:40 - 09:20 am 

AE Ron Weiss, Massachusetts Institute of Technology, USA
Mammalian synthetic biology: programmable organoids, machine learning, and neuromorphic computing in cells

09:20 - 10:00 am 

AE Victor de Lorenzo, Centro Nacional de Biotecnología, Spain
SynBio tools for engineering new-to-nature interactions in microbial communities

10:40 - 11:20 am 

Petra Schwille, Max Planck Institute of Biochemistry, Germany
Autonomous positioning of a division ring in minimal cells



December 16

(Moderator: José R. Dinneny, Stanford University)

08:00 - 08:40 am 
US Pacific Standard Time

Nicola Patron, The Earlham Institute, UK
Recoding Regulation:Synthetic Expansions of Plant Metabolism

08:40 - 09:20 am 

José R. Dinneny, Stanford University, USA
Making phenotypes: using robotics and synthetic genetic circuits to characterize and engineer root system architecture

09:20 - 10:00 am 

Alison Smith, University of Cambridge, UK
Redesigning the Chlamydomonas chloroplast genome

10:00 - 10:40 am 

Matias Zurbriggen, Heinrich Heine University Düsseldorf, Germany
Photoreceptor engineering for ontogenetic control and study of signalling and metabolic processes in animal, microbial and plant Systems.

10:40 - 11:20 am

AE Anke Becker, Philipps University of Marburg, Germany
ECFexpress: an orthogonal, organism-independent expression platform based on extracytoplasmic function (ECF) sigma factors

11:20 - 12:00 pm 

EiC Xiaohan Yang, Oak Ridge National Laboratory, USA
Perspectives on the application of plant synthetic biology in climate change mitigation



December 17

Closing ceremony (Moderator: Megan J. Palmer, Stanford University, USA)

08:00 - 08:40 am
US Pacific Standard Time

AE Diane DiEuliis, National Defense University, USA
Expanding Biosecurity by Design

08:40 - 09:20 am

AE Gigi Kwik Gronvall, Johns Hopkins University, USA
Biodesign security, safety, and social responsibility

09:20 - 10:00 am

Megan J. Palmer, Stanford University, USA
Biodesign from molecular to social scales

10:00 - 10:40 am

Closing remarks by the conveners and Poster award

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Contact us

Venue & Accommodation: Qiaoning He, 13871293198; Qian Li, 13419638706
Speakers: Wanping Chen, 13163296238; Huili Yu, 15063678320
Abstract & Poster: Xia Wang, 18817517865
Sponsors: Tianye Li,15527076291
Payment and invoice: Huan Wang, 13588474548
Register: Lucy Wang, info@biodesignresearch.com, +86 177 0518 5080

Address:5 Tongwei Road, Xuanwu District, Nanjing, Jiangsu Province, China 

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